Question |
Answer |
What is ontogeny? |
the series of developmental phenomena that occurs as the organism progresses toward sexual maturity |
What are 2 main processes of gametogenesis? |
1. spermatogenesis which produces 4 spermatozoa and 2. oogenesis which produces 1 ovum and 2-3 polar bodies |
During spermatogenesis, the ____________ which is _________ undergoes mitosis and produces ________ which then under meiosis |
spermatogonium. diploid. spermatocytes. |
During Oogenesis, the _______ undergoes mitosis and produces ______ which undergo meiosis to make egg cells |
oogonium. oocytes. |
What 3 parts make up a single sperm? |
1. head which contains the haploid genome and acrosome with digestive enzymes, 2. neck/midpiece with mitochondria, and 3. tail |
What 2 parts make up an egg cell? |
1. The cell itself, which has a haploid genome, nutrition and energy reserves for embryo, and the egg itself has polarity. 2. Outer membranes and layers |
What are model organisms? |
They are advantageous for studying aspects of development, usable as external fertilizers and produce many progeny and large eggs. |
What 2 membranes make up the ECM of yolk? |
1. vitelline membrane and 2. jelly coat |
What happens during fertilization? |
A zygote is produced and diploid state is restored and development is activated |
What polarity do humans have? What about other animals? |
Humans have D-V polarity and other animals have A-V polarity |
What is embryogenesis and what 3 phases does it consist of? |
the process in which the metazoan forms, 3 phases are cleavage, gastrulation, and organogenesis |
What is cleavage? |
A phase of rapid cell division and zygotes that divides to form cells called blastmeres |
What are 2 main types of cleavages? |
Meroblastic cleavage- partial furrow and high yolk content and holoblastic cleavage- entire furrow with moderate yolk content |
Cleavage results in the formation of the ______ |
blastula |
What is a blastula? |
A hollow ball of cells that contains the blastocoel |
What is gastrulation? |
The global reorganization of the embryo |
What are the outcomes of gastrulation? |
The formation of the germ layers and the proper spatial arrangement of germ layers, and establish the body plan |
Organisms with 3 germ layers are known as? Organisms with 2 germ layers are known as? |
Triploblasts and diploblasts |
What are the 3 main layers that is formed from the blastoma called? |
Ectoderm, endoderm and mesoderm |
What does the ectoderm form? |
Epidermal ectoderm and central nervous system |
What does the mesoderm form? |
Muscle connective tissues and coelomic linings |
What does the endoderm form? |
the digestive system epithelium |
Organization of germ layers during gastrulation produces what 2 things? |
1. the archenteron and 2. the blastopore |
In triploblasts, protostomes form what first? |
the blastopore forms the mouth first and then the anus second |
In triploblasts, deuterostomes form what first? |
the blastopore forms the anus first and then the mouth |
How are organs formed? |
Formed locally within the embryo and each layer is divided into germ layer regions associated with organ contributions |
What are indirect developers? |
A reproductively immature organism that appears dissimilar from mature adult that exists as a larva and undergoes metamorphosis before becoming an adult |
What are direct developers? |
A reproductively immature organism that appears similar to the adult and growth is mainly involved without dramatic changes |
What 4 main mechanisms direct the process of embryogenesis? |
1. Polarity, 2. morphogenesis, 3. inductive interactions, and 4. restrictions of developmental potential with differentiation as final realization of developmental program |
What is polarity? |
"Instructions" that are segregated in the zygote |
What is morphogenesis? |
Changes in the cell that results in changes in tissue |
What is inductive interactions? |
Communications between cells |
What is Cell fate determined by? |
They become restricted over time and differentiation occurs as a result to make cells specialized for certain purposes |
What are determinants primarily used for? |
They consist of mRNAs and proteins and are equally distributed in the egg and/or distributed to particular regions within the egg |
What key piece of evidence shows that the body plan is established at fertilization? |
The gray crescent |
Morphogenesis involves what 3 changes? |
1. Changes in cell or tissue shape and 2. changes in cell or tissue adhesion, and 3. changes in the position of cells or tissues within the embryo via migration |
What is invagination? |
The inward buckling of cells to form a pocket |
What is involution? |
The inward rolling of cells over an edge |
What is epiboly? |
The spreading of cells over an external surface |
What is ingression? |
The transition of cells from an epithelial to a mesenchymal state while migrating inward |
What is neurulation? |
The series of morphogenetic events involved in formation of the vertebrate central nervous system |
What is adhesion of cells in morphogenesis? |
It involves the interactions of a cell with other cells and a cell with its extracellular matrix environment |
Adhesion is mediated what 2 kinds of transmembrane proteins? |
1. Cadherins that mediate cell-cell interactions and 2. integrins mediate cell-ECM contacts with adhesive glycoproteins |
Inductive interactions involve _________ _________ in which cells give instructions for development. This involves the use of paracrine signaling called ______ ______ |
intercellular communications. growth factors. |
What experiment did Spemann and Mangold demonstrate? |
They demonstated the presence of globally-acting inductions in amphibians |
What drives limb formation? |
Localized, reciprocal inductions |
What drives limb polarity? |
Inductive interactions |
What is differentiation? |
Cells becoming specialized for a specific fate and remain that way for the rest of an organism's life. |